Research

Presently, our lab has three research paths: 1) macromolecular crystallization and methodology; 2) structure and function of thermophilic proteins; and 3) inflammation and chronic stress sensitivity/resiliency. The basic research focus has been growing large volume crystals for neutron diffraction and investigating the structure-based catalytic mechanism of enzymes related to phosphoryl-transfer reactions. Our recently established research path includes the utilization of immunological and molecular approaches to study proteins and nucleic acids associated with inflammation and chronic stress sensitivity/resiliency

Crystallization and methodology

Large volume Inorganic Pyrophosphatase grown onboard the International Space Station.

Macromolecular structure and function

Structure-based mechanism of phosphoryl-transfer in Inorganic Pyrophosphatase from T. thermococcus.

Chronic stress sensitivity/resiliency and inflammation

Inflammation-related Human Δ5 desaturase (D5D)

Present research funding

Current support for research funding is provided by:

Inner Defense

Little Orange Fish

Everett George Daily Foundation

iXpressGenes/All Points-U.S. AirForce U.S. Air Force mentor-protégé program.