Historical research highlights

Selected historical research highlights for the Ng lab are shown below. Recent works are not shown here.

Voyages in the Atlantic and Pacific Oceans on board the Akademik Mstislav Keldysh in search of extremophiles (1999-2003)

Sample collection at the Rainbow hydrothermal vent, Mid-Atlantic Ridge (1999)

Newly cultured and identified hyperthermophilic sulfur-reducing archaeon, Thermococcus thioreducens (strain OGL-20P) from the Rainbow vent. Genome sequenced.(2007)

High-throughput gene to structure pipeline established for the Southeast Collaboratory for Structural Genomics (2002)

In situ data collection of crystals grown counter-diffusion (2002)

First ab initio crystallographic structure determination of protein crystals gown by counter-diffusion equilibration without crystal handling (2002)

First anomalous difference electron-density maps calculated from in situ x-ray data collection of protein crystals grown by counter-diffusion (2003)

First high though-put counter-diffusion instrument for structural genomics applications (2006)

First large volume protein crystals obtained by counter-diffusion crystallization for neutron crystallography (2015).

Commercial activities

Founded ExtremoZyme with UAH in commercializing products and services related to extremophiles (2006).

ExtremoZyme became iXpressGenes and is based in the HudsonAlpha Institute for Biotechnology. (2008)